Therapeutic antibodies like Nivolumab have revolutionized cancer care, offering new hope to patients across the globe. However, the success of these therapies heavily depends on accurate pharmacokinetic (PK) monitoring and that is where Denovo Biolabs comes in.
Our Nivolumab PK ELISA Kit is designed to support clinical researchers, CROs, and biopharma partners in quantifying Nivolumab levels with high sensitivity and specificity, enabling better dosing strategies and robust clinical data collection.
Why Pharmacokinetic Monitoring matters in Immunotherapy?
Nivolumab, an anti–PD-1 checkpoint inhibitor, plays a key role in modulating the immune response against tumours. However, variability in patient response, risk of immunogenicity, and dosing efficacy all necessitate close monitoring of circulating drug levels.
Key applications of Nivolumab PK monitoring include:
- Dose optimisation during clinical trials and therapy
- Correlation of drug levels with therapeutic outcomes
- Assessment of immunogenic responses
- Biosimilar comparability studies
Features of Denovo’s Nivolumab PK ELISA Kit
Our ELISA kit is a sandwich-based immunoassay optimised for serum and plasma samples.
Kit Components:
- Pre-coated 96-well microplate
- Nivolumab standards & quality controls
- Detection antibody & HRP-conjugate
- Substrate & stop solution
- Wash buffer & sample diluent
Analytical Highlights:
| Parameter | Value |
|---|---|
| Assay Type | Sandwich ELISA |
| Sample Type | Human Serum / Plasma |
| Detection Range | 0.1–25 µg/mL |
| Sensitivity | < 0.1 µg/mL |
| Intra-assay CV | < 10% |
| Inter-assay CV | < 12% |
Visualising Performance
Below is the standard curve obtained with serial dilutions of Nivolumab. This curve demonstrates excellent linearity and reproducibility across the dynamic range:
Built for CROs, biopharma & academic labs
If you are a contract research organisation, clinical-stage biotech company, or academic institute exploring checkpoint inhibitor dynamics, this kit helps you:
- Speed up preclinical and clinical workflows
- Ensure assay reproducibility
- Maintain regulatory-compliant documentation
Denovo’s in-house manufacturing and QC processes ensure that every lot meets the highest scientific and operational standards. Our kits are validated to be “fit for purpose” in both GLP and non-GLP settings.
Proudly designed and manufactured in India
At Denovo Biolabs, we are not just building products, we are building a biotech ecosystem. Our mission is to make affordable, high-quality analytical tools available to the Indian and global market alike.
By choosing Denovo, you are investing in:
- Indigenous innovation 🧠
- Scalable biotech infrastructure ⚙️
- Global-quality diagnostics, made locally 🌏
Ready to explore the kit?
If you are working in oncology R&D, biosimilar development, or need robust PK data for regulatory filing, this kit is made for you.
Contact Us to request a data sheet, place an order, or get pricing support.
Let’s simplify immunotherapy analytics together 🤝